Bilateral Knee Osteoarthritis
Conditions
Brief summary
Treatment: five intro-articular Hyaluronic Acid injection Assessment has two parts, that are as follow: 1. Postural stability and risk of fall assessment using Biodex stability index and Timed up and Go test 2. Gait and stair climbing assessment using Vicon motion capture system synchronized with four force plates. For knee OA subjects, assessment was done in week one or before injection; and for healthy controls one assessment was performed.
Detailed description
This study aimed to assess the effect of hyaluronic acid injection on Postural stability, biomechanics of gait and stair climbing in individuals with bilateral knee osteoarthritis (OA). Participants were individuals with knee OA (control and treatment) and healthy people.
Interventions
OTHERHyaluronic acid
treatment: Weekly intra-articular hyaluronic acid injection (20 MG / 2ML) into both knees for five weeks.
Sponsors
University of Malaya
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
50 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Mild and moderate bilateral knee osteoarthritis * Age between 50 and 70 years
Exclusion criteria
* Recent Lower limb injury * Diabetic * Knee or hip replacement * Knees HA injection in last 6 months * Any neuromuscular disease such as stroke and Parkinson
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Postural stability after treatment | baseline and 6 weeks |
| Changes in Biomechanics of gait after treatment | baseline and 6 weeks |
| Changes in biomechanics of stair climbing after treatment | baseline and 6 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Change in Pain after treatment | baseline and 6 weeks |
| Changes in WOMAC scores after treatment | baseline and 6 weeks |
Outcome results
None listed