Attention Deficit Disorder
Conditions
Keywords
attention deficit disorder (ADHD), cognitive behavioral therapy (CBT), adult
Brief summary
The purpose of this study is to determine whether cognitive behavioral therapy (CBT) is effective in the treatment of attention deficit and emotional, executive function and social function dysregulation due to attention deficit disorder (ADHD).
Detailed description
Participations will be randomly assigned to 3 groups which are CBT with booster sessions group, CBT only group and waiting group.With the comparison of first tow groups we will explore the effect of booster sessions, and the last two groups the effect of CBT programme.
Interventions
BEHAVIORALCBT only
Participants will learn 12 sessions including educational information about ADHD and skills in organization and plan, reducing distractibility, and adaptive thinking.
BEHAVIORALCBT with booster sessions
Participants are provided with the same CBT programme and additional 3 booster sessions which summarize and extend the 3 main topics of the CBT programme in order to improve the skills practice ability.
Sponsors
Peking University Sixth Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Outpatients from Peking University Sixth Hospital * Diagnosis of adult ADHD based on Diagnostic and statistical manual of mental disorders, Fourth Edition (DSM-IV) * Stable on medications for adult ADHD for at least 2 months
Exclusion criteria
* Severe major depression, clinically significant panic disorder, bipolar disorder, organic mental disorders, psychotic disorders, or pervasive developmental disorders * Intelligence Quotient (IQ) less than 90 * Suicide risk * Unstable physical condition * Prior participation in cognitive behavioral therapy for ADHD or other psychological therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in ADHD Rating Scale | Baseline, at the end of week 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 11 in treatment, 12 weeks (post), 24 weeks (FU6), 36 weeks (FU9), and 48 weeks (FU12) | ADHD symptom severity as measured by the ADHD rating scale (DuPaul, et al., 1998) a scale that ranges from 0-54 with 0 indicating lower severity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Self-Rating Anxiety Scale (SAS) | Baseline, at the end of week 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 11 in treatment, 12 weeks (post), 24 weeks (FU6), 36 weeks (FU9), and 48 weeks (FU12) | The Self-Rating Anxiety Scale (SAS) with 20 items measures the level of anxiety. |
| Change in Self-rating depression scale (SDS) | Baseline, at the end of week 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 11 in treatment, 12 weeks (post), 24 weeks (FU6), 36 weeks (FU9), and 48 weeks (FU12) | The Self-rating depression scale (SDS) is used to measure the level of depression. |
| Change in Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A) | Baseline, 12 weeks (post), 24 weeks (FU6), and 48 weeks (FU12) | The BRIEF-A measures the impairment level of executive function in ADHD adults. |
| Change in Cambridge Neuropsychological Test Automatic Battery (CANTAB) | Baseline, 12 weeks (post), 24 weeks (FU6), and 48 weeks (FU12) | The CANTAB is a computerized neuropsychological test measuring the cognitive and executive function. |
| Change in Conners Adult ADHD Rating Scale Self-report Screening Version (CAARS-S:SV) | Baseline, at the end of week 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 11 in treatment, 12 weeks (post), 24 weeks (FU6), 36 weeks (FU9), and 48 weeks (FU12) | The CAARS-S:SV is a self-reported scale measures the ADHD symptom severity including 30 items rating from 0 to 3. |
| Change in self-esteem scale (SES) | Baseline, 12 weeks (post), 24 weeks (FU6), and 48 weeks (FU12) | The self-esteem scale measures the level of self-esteem. |
| Change in World Health Organization Quality of Life-Brief Version (WHOQOL-BREF) | Baseline, 12 weeks (post), 24 weeks (FU6), and 48 weeks (FU12) | The WHOQOL-BREF is the short version of World Health Organization Quality of Life scale and includes 26 items measuring the level of life quality. |
| Change in Brain Oxygenation Level Dependent (BOLD) Signal | Baseline, 12 weeks (post) | The level of BOLD activity during working memory task after CBT is compared with baseline level to explore the potential effects of CBT on brain. |
| Change in Barratt impulsiveness scale (BIS) | Baseline, 12 weeks (post), 24 weeks (FU6), and 48 weeks (FU12) | The Barratt impulsiveness scale including 30 items is used to measure impulsiveness. |
Countries
China
Outcome results
None listed