Calcinosis, Scleroderma
Conditions
Keywords
scleroderma, calcinosis
Brief summary
This is a 10 year study of scleroderma patients with calcinosis 1) to better understand how common and if there are any risk factors for having calcinosis 2\) to identify common complications associated with scleroderma-related calcinosis. .
Detailed description
This is a prospective study of scleroderma- spectrum patients focused on soft tissue calcinosis in order 1) to better understand the risk factors (including clinical/laboratory characteristics, and serology) of calcinosis in the scleroderma-spectrum disorders (limited or diffuse systemic sclerosis with or without overlap of inflammatory arthritis and/or myositis). 2\) view common complications associated with calcinosis. Better understanding of scleroderma calcinosis would lead to other studies that eventually will define better treatment options for this incurable and often disabling complication.
Interventions
None listed
Sponsors
Rutgers, The State University of New Jersey
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Adult scleroderma subjects with and without calcinosis
Exclusion criteria
* Subjects unwilling to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| risk factors and outcomes in scleroderma calcinosis | 10 years | This is an observational study of scleroderma calcinosis to assess possible risk factors (including serologic studies and disease types) as well as common complications that occur in those with scleroderma calcinosis during this time period. We will assess for increased burden of calcinosis with associated musculoskeletal complications from calcinosis over 10 years. No additional intervention will be delivered, other than standard of care for this complication. |
Countries
United States
Outcome results
None listed