We Focus on the Pain of Venipuncture and Intravenous Cannulation
Conditions
Keywords
Lidocaine patches, Pain, Intravenous cannulation
Brief summary
Venipuncture and intravenous cannulation are the most common painful procedures, especially for the penitents who must receive large diameter venous catheter before surgery. In present study we would evaluate the safety and validity of lidocaine patches releasing such pain.
Interventions
Sponsors
Nitto Denko Corporation
Giant Med-Pharma Services Inc.
RenJi Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients who want to participate present study and sign the informed consent form * Age from 18 to 65 years old * Patients who need intravenous cannulation before surgery * ASA class I-II and selected patients
Exclusion criteria
* Allergic to lidocaine or any other amide local anesthetics or any other medicine * Allergic skin(allergic to past agent or other topical used medicine) * Skin injured or inflection exist in the local site to patch * Sensation disturbed in any limb * Severe liver and kidney original disease:blood Aspertate aminotransferase and Alanine transaminase increased 1.5 times more than normal concentration; blood creatinine is higher than the normal range. * Hemoglobin \<80g/L * ECG is significantly abnormal * pregnant or possible pregnant or breastfeeding woman * Patient who has consciousness disturbance can not make credible dialog with investigator. * Those who are using other medicine may affect the evaluation of present patch * Those who have participated in other clinical trail in the past three months * Those excluded by investigator believed other reasons.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The efficiency of lidocaine patches for attenuating the pain of venipuncture intravenous cannulation before surgery | Two minters after intravenous cannulation | VAS score will be evaluated two minters after intravenous cannulation in both group with lidocaine patches or not. |
| Skin response after intravenous cannulation | Thirty minters after intravenous cannulation | Local skin response to the lidocaine patches will be evaluated thirty minters after intravenous cannulation |
Countries
China
Contacts
Primary ContactDiansan Su, Dr.
Outcome results
None listed