MADIT-CRT LONG-TERM INTERNATIONAL FOLLOW-UP REGISTRY - EUROPE

Conditions

Heart Failure

Keywords

CRT, HEART FAILURE

Brief summary

The registry is designed to determine the long-term mortality and morbidity benefit as a result of Cardiac Resynchronization Therapy with Defibrillation (CRT-D) vs. Implantable Cardioverter Defibrillator (ICD) therapy in the MADIT-CRT study patient population. The registry will collect data on patients that previously participated at MADIT-CRT sites within Europe through five years of participation from their orginal enrollment in the MADIT-CRT IDE study.

Himabindu Vidula, Elizabeth Lee, Scott McNitt, Bronislava Polonsky, Mehmet K. Aktaş et al. (11 authors)

Circulation Heart Failure2020-07-014 citations

10.1161/circheartfailure.120.006925

Long-term Outcomes of Cardiac Resynchronization Therapy by Left Ventricular Ejection Fraction

Valentina Kutyifa, Katherine Vermilye, Scott D. Solomon, Scott McNitt, Arthur J. Moss et al. (6 authors)

European Journal of Heart Failure2018-12-287 citations

10.1002/ejhf.1357

Left Ventricular Lead Location and Long-Term Outcomes in Cardiac Resynchronization Therapy Patients.

Kutyifa V, Kosztin A, Klein HU, Biton Y, Nagy VK, Solomon SD, McNitt S, Zareba W, Goldenberg I, Roka A, Moss AJ, Merkely B, Singh JP.

2018-08-2913 citations

10.1016/j.jacep.2018.07.006

Predictors and Risk of Ventricular Tachyarrhythmias or Death in Black and White Cardiac Patients: A MADIT-CRT Trial Substudy.

Sabbag A, Goldenberg I, Moss AJ, McNitt S, Glikson M, Biton Y, Jackson L, Polonsky B, Zareba W, Kutyifa V.

2016-05-1818 citations

10.1016/j.jacep.2016.03.003

Relation of QRS Duration to Clinical Benefit of Cardiac Resynchronization Therapy in Mild Heart Failure Patients Without Left Bundle Branch Block

Yitschak Biton, Valentina Kutyifa, Iwona Cygankiewicz, Ilan Goldenberg, Helmut Klein et al. (11 authors)

Circulation Heart Failure2016-02-0118 citations

10.1161/circheartfailure.115.002667

Sex Differences in Long‐Term Outcomes With Cardiac Resynchronization Therapy in Mild Heart Failure Patients With Left Bundle Branch Block

Yitschak Biton, Wojciech Zaręba, Ilan Goldenberg, Helmut Klein, Scott McNitt et al. (8 authors)

Journal of the American Heart Association2015-07-1750 citations

10.1161/jaha.115.002013

Long-Term Outcomes With Cardiac Resynchronization Therapy in Patients With Mild Heart Failure With Moderate Renal Dysfunction

Usama A. Daimee, Arthur J. Moss, Yitschak Biton, Scott D. Solomon, Helmut Klein et al. (10 authors)

Circulation Heart Failure2015-06-0320 citations

10.1161/circheartfailure.115.002082

Survival with Cardiac-Resynchronization Therapy in Mild Heart Failure

Ilan Goldenberg, Valentina Kutyifa, Helmut Klein, David S. Cannom, Mary W. Brown et al. (24 authors)

New England Journal of Medicine2014-03-30348 citations

10.1056/nejmoa1401426

Interventions

DEVICEPatients that were randomized to the the cardiac resynchronization therapy with defibrillation (CRT-D) device for the study

DEVICEMADIT-CRT ICD ONLY ARM

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

No

Inclusion criteria

Active patients who were enrolled in the MADIT-CRT IDE within Europe

Exclusion criteria

Patients who are unable or unwilling to comply with the protocol requirements

Design outcomes

Primary

Measure	Time frame
All-cause mortality	36 month follow-up

Secondary

Measure	Time frame	Description
Heart failure event or death	36 month follow-up	The combined end point of heart-failure or death, whichever came first.

Countries

Israel

Outcome results

None listed