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Prevention Ventilator Associated Pneumonia

Impact of 4 Sequential Measures on the Prevention of Ventilator Associated Pneumonia in Major Heart Surgery Intensive Care Unit

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02060045
Acronym
REINA
Enrollment
1534
Registered
2014-02-11
Start date
2009-11-30
Completion date
2012-06-30
Last updated
2014-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator-associated Pneumonia

Keywords

bundle, prevention, Disturbance; Heart, Functional, Postoperative, Cardiac Surgery

Brief summary

The objective of the investigators work was to evaluate the impact of 4 sequentially implemented measures for preventing VAP in a major heart surgery ICU. The measures were a specific training program, aspiration of subglottic secretions (ASS), introduction of an inclinometer to improve the semirecumbent position, and reinforcement of oral care with chlorhexidine.

Interventions

OTHERBundle implementation

Sponsors

Ciber de Enfermedades Respiratorias
CollaboratorUNKNOWN
Fundación Rafael del Pino
CollaboratorUNKNOWN
Fondo de Investigacion Sanitaria
CollaboratorOTHER
Maria Jesus Perez
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* all patients with heart surgery admitted in critical care unit during the study period

Exclusion criteria

* none

Design outcomes

Primary

MeasureTime frameDescription
Change (reduction) in the incidence density of Ventilator associated pneumonia (VAP)Baseline and up to 35 monthsChange (reduction) in the incidence density of VAP

Secondary

MeasureTime frame
Change(length) in Intensive Care Unit (ICU) stayBaseline and up to 35 months
Change (number of days) in Mechanical Ventilator (MV) per ICU stayBaseline and up to 35 months
Change in mortality rateBaseline and up to 35 months
Change in cost of antimicrobial acquisition during ICU stayBaseline and up to 35 months
Change in compliance with the measuresBaseline and up to 35 months

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 8, 2026