Urinary and Sexual Function Before and After Surgical Decompression of Cervical Myelopathy

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02059798

Enrollment

Registered

2014-02-11

Start date

2014-03-31

Completion date

2016-08-31

Last updated

2014-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erectile Dysfunction, Myelopathy, Neurogenic Bladder, Psychosexual Dysfunctions, Sexual Arousal Disorder

Keywords

Myelopathy

Brief summary

Hypotheses: Decompressive surgery of cervical myelopathy will improve bladder function. Decompressive surgery of cervical myelopathy will improve sexual function.

Detailed description

The investigators will enroll consecutive cohort with cervical myelopathy who are scheduled to take surgical decompression of cervical spinal cord, aged between 25 and 65. The exams for the patients include followings * JOA (Japanese Orthopaedic Association) Scores for cervical myelopathy * VAS (Visual Analog Scale) pain score * IPSS (International Prostate Symptom Score) and IIEF (International Index of Erectile Function) in male patients * FSFI (Female Sexual Function Index) and UDI (Urinary Distress Inventory) in female patients * Bladder compliance, Detrusor leak point pressure, Peak detrusor pressure * Rigidity activity unit of penis

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

25 Years to 65 Years

Healthy volunteers

Inclusion criteria

* evidence of progression of motor or sensory nerve * cervical myelopathy in magnetic resonance imaging

Exclusion criteria

* radical pelvic surgery * pelvic irradiation * evidence of brain damage (dementia, cerebrovascular disease) * evidence of psychotic disorder

Design outcomes

Primary

Measure	Time frame	Description
JOA (Japanese Orthopaedic Association) Scores for cervical myelopathy	6 months after surgery	This score will provide patients' conditions at a glance.

Secondary

Measure	Time frame	Description
Bladder compliance	6 months after surgery	This will be provided by urodynamic study, and will show the intactness of Guarding reflex from upper spinal cord tract.

Other

Measure	Time frame	Description
Rigidity activity unit of penis	6 months after surgery	This study will be provided by nocturnal penile tumescence study and will show the intactness of psychogenic erectile pathway.
Female sexual function index	6 months after surgery	This will show the female patients' sexual arousal state.

Countries

South Korea

Contacts

Primary ContactDong Sup Lee, MD, PhD

lds@catholic.ac.kr82-31-249-8276

Backup ContactIlsup Kim, MD, PhD

nsman72@hanmail.net82-31-249-7190

Outcome results