Cataract
Conditions
Keywords
Retained nuclear lens fragments, Phacoemulsification, Cataract Surgery
Brief summary
The purpose of this study is to investigate postoperative events in patients noted to have retained nuclear fragments in the anterior vitreous during routine phacoemulsification and in those who did not.
Detailed description
In this study, we investigate whether presence of retained nuclear fragments in the anterior vitreous noted during uncomplicated cataract surgery is associated with higher incidence of postoperative adverse events. We will be assessing events including cystoid macular edema, iritis, elevated intraocular pressure, and retinal detachment.
Interventions
PROCEDUREPhacoemulsification
Subjects will be recruited serially from eligible candidates on the basis of presentation for cataract evaluation and subsequent cataract surgery with phacoemulsification.
Sponsors
Ophthalmic Consultants, Corneal and Refractive Surgery Associates, PC
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Routine cataract surgery with phacoemulsification
Exclusion criteria
* Pre-existing macular edema * Active uveitis * Intraocular exclusion surgeries * Significant ocular trauma * Evidence of phacodonesis or zonular weakness .
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Macular edema | 1 month postoperatively | Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 1 month postoperatively |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intraocular inflammation | 1 month postoperativley | Proportion of eyes with persistent anterior chamber inflammation requiring medical treatment at 1 month postoperatively |
| Elevated intraocular pressure | 1 month postoperatively | Proportion of eyes with intraocular pressure increase requiring medical or surgery treatment at 1 month postoperatively |
| Intraocular Inflammation | 1 week postoperatively | Proportion of eyes with persistent anterior chamber inflammation requiring medical treatment at 1 week postoperatively |
| Elevated Intraocular Pressure | 1 week postoperatively | Proportion of eyes with intraocular pressure increase requiring medical or surgery treatment at 1 week postoperatively |
| Macular Edema | 1 week postoperatively | Proportion of eyes with clinical macular edema and subclinical macular edemas measured by OCT at 1 week postoperatively |
Other
| Measure | Time frame | Description |
|---|---|---|
| Surgical Complications | Intraoperatively | Proportion of eyes with surgical adverse events. |
Countries
United States
Outcome results
None listed