Dental Cavity
Conditions
Keywords
Bacteria, microbial community, hygiene
Brief summary
The primary objective of this study is to estimate the distribution of pathogenic species and genotypes of bacterial diversity in 7 stages ICDAS (International Caries Detection and Assessment System) corresponding to the severity of dental caries among patients aged 3-45 years consulting in the Dentistry Departments of the Nîmes University Hospital and the Montpellier University Hospital.
Detailed description
Secondary objectives include: * Compare the distribution of bacterial species in relation to stages of severity of caries * Compare the results from plaque with those of saliva samples.
Interventions
OTHERDental cavity evaluation
The dental cavities present will be evaluated using the ICDAS (International Caries Detection and Assessment System).
BIOLOGICALSaliva sampling
A saliva sample will be harvested.
BIOLOGICALPlaque sampling
Plaque samples from a healthy tooth and a tooth with a cavity will be harvested.
Sponsors
Centre Hospitalier Universitaire de Nīmes
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
3 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Volunteers aged 3 to 45 who come in to the hospital for a dental consultation * Minors must have parental permission * The patient must have given his/her informed and signed consent
Exclusion criteria
* The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is pregnant, or breastfeeding * The patient has been on antibiotics within the past two months * Smokers * Teeth under current care * Parodontopathy * Use of a mouthwash within the last week * Insufficient numbers of healthy and/or teeth with carious lesions for carrying out the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ICDAS assessment | Baseline (day 0) | Dental caries will be assessed using the ICDAS (International Caries Detection and Assessment System) system |
| Bacterial profile | Baseline (day 0) | Bacterial profiles will be constructed using saliva and plaque samples. |
Secondary
| Measure | Time frame |
|---|---|
| Does the patient have at least five fillings? yes/no | Baseline (day 0) |
| Does the patient have at least one filling and one missing tooth on the anterior sector following the carious lesion? yes/no | baseline (day 0) |
| Within the last 12 months, the patient has had dental care or tooth removal following the carious lesion? yes/no | baseline (day 0) |
| Yesterday, did the patient eat at least three snacks (or sugary or carbonated drinks) between meals? yes/no | Baseline (day 0) |
| Studies were stopped during high school? yes/no | baseline (Day 0) |
| The patient has at least one carious lesion restricted to the enamel on an anterior tooth or involving the smooth surface on a posterior tooth (yes/no) | baseline (day 0) |
| The patient has at least one carious lesion attacking the dentin or pulp. yes/no | baseline (day 0) |
| The patient has at least one carious lesion reaching dentin or pulp on an anterior tooth or on the smooth surface of a posterior tooth (yes/no) | baseline (day 0) |
| Yesterday, did the patient brush his/her teeth fewer than 2 times? yes/no | baseline (day 0) |
| The patient has at least one carious lesion restricted to the enamel? yes/no | baseline (day 0) |
Other
| Measure | Time frame |
|---|---|
| Profession (or parents' professions) | baseline (day 0) |
| Age | baseline (day 0) |
| Sex | baseline (day 0) |
Countries
France
Outcome results
None listed