TIMP-2 and IGFBP7 for the Prediction of the Cardiac Surgery Associated Acute Kidney Injury

Novel Biomarkers (TIMP-2 and IGFBP7) of Tubular Renal Cell Damage for the Prediction of the Cardiac Surgery Associated Acute Kidney Injury (CSA-AKI) - A Feasibility Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02054546

Enrollment

110

Registered

2014-02-04

Start date

2013-12-31

Completion date

2014-12-31

Last updated

2015-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Brief summary

The purpose of this study is to analyze the new biomarkers (TIMP-2 and IGFBP-7) of tubular renal cell damage for the prediction of the Cardiac Surgery Associated acute kidney injury.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* planned cardiac surgery

Exclusion criteria

* renal dialysis * minors * emergency * no cardiopulmonary bypass

Design outcomes

Primary

Measure	Time frame
AKI-stadium 1 (KDIGO)	30 days

Secondary

Measure	Time frame
all cause mortality	30 days

Other

Measure	Time frame
AKI Stadium 2-3 (KDIGO)	30 days

Countries

Switzerland

Outcome results