Preterm Milk, Term Milk
Conditions
Brief summary
This study aims for an in-depth characterization of human milk of mothers who delivered prematurely to decipher differences with milk of mothers who delivered at the expected term, with a particular focus on milk proteins
Interventions
None listed
Sponsors
Société des Produits Nestlé (SPN)
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Having obtained informed consent * Group 1 (term delivery): Gestational age between 37 0/7 and not above 41 6/7 weeks * Group 2 (preterm delivery): Gestational age between 28 0/7 and 32 6/7 weeks * Age: Mother ≥ 18 years old * Partial or total breast feeding * Having a freezer compartment at home (approx. -18°C) * Good understanding of the French language
Exclusion criteria
* Suffering from diabetes (type I or II) before pregnancy * Alcohol consumption: more than 1 standard drink / day * Drug addicted * Subject who cannot be expected to comply with the study procedures. * Currently participating in an interventional therapeutic clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantification of total protein concentration in human milk | from delivery, up to 4 months |
Secondary
| Measure | Time frame |
|---|---|
| Quantification of total lipids and carbohydrates | From delivery, up to 4 months |
| Determination of Calcium and Phosphorous content | From delivery, up to 4 months |
| Determination of peptide profiles and content | From delivery, up to 4 months |
| Determination of miRNA content | From delivery, up to 4 months |
Countries
Switzerland
Outcome results
None listed