The Sensitivity and Specificity of Sniff Dog as a Tool in Diagnosing the Suspected Tumor Patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02049658

Enrollment

2000

Registered

2014-01-30

Start date

2014-01-31

Completion date

2026-12-31

Last updated

2024-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neoplasia

Keywords

tumor, cancer

Brief summary

Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces. It is hypothesized that sniff dogs may be used as a tool in identifying cancer patients in the high risk population or suspected patients. Trained dogs will sniff serum from participants who are suspected to suffer from tumor by their physicians and not yet but will be diagnosed by pathological examination.The results will be compared with the outcome of the pathological examination.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Healthy volunteers who have been examined by the currently used procedures and find to be without tumors. * Patients in the breast surgery, thoracic surgery, gynecological and neurosurgery departments with lesions with characteristics of tumors

Exclusion criteria

* Patients who have had pathological results

Design outcomes

Primary

Measure	Time frame	Description
sensitivity and specificity of the sniff dogs as a tool in diagnosing tumors	12 months	The results that obtained from the dogs will be compared with these of the pathological examinations. Sensitivity = the No. of patients identified by the dogs as cancers / the No. of patients suffering from cancer confirmed by pathological examination. Specificity = No. of subjects signaled by the dog as non-cancers / No. of subjects confirmed by pathological examination as non-cancer subjects.

Secondary

Measure	Time frame	Description
behavior patterns of the sniff dogs to different diseases	12 months	The behavior (lying before the tank for positive, neglecting the tanks) of the dog will be recorded and compared with the results of the pathological examination.

Other

Measure	Time frame	Description
the substances used for identifying tumors by the sniff dogs	12 months	GCMS etc will be used to compare the volatile compounds between the sera from cancers patients and the from non-cancer subjects, the suspected VOCs will be tested by the dog for conformation.

Countries

China

Contacts

Primary ContactChang-Qing Gao, MD PhD

cgao851@126.com86 188 7486 9488

Backup ContactYa-Qin Wang, MD PhD

wdove.bb@163.com86 15274810930

Outcome results