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Hemodynamic Measurements at Different Inclinations of the Head

Comparison of CVP Values , ΔPP and Echocardiographic at Different Angles Headwaters Before and After Volume Challenge

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02046785
Acronym
HMDIH
Enrollment
30
Registered
2014-01-28
Start date
2013-04-30
Completion date
2014-05-31
Last updated
2014-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypovolemic Shock

Keywords

Fluid administration, Cardiac output, Right atrial pressure, Resuscitation

Brief summary

The purpose of this study is to determine whether hemodynamic measures vary in angles bedside before and after volume challenge.

Detailed description

* Check if values of central venous pressure (CVP), pulse pressure variation (Δpp), heart rate (HR), mean arterial pressure ((PAM) vary in different angles headboards * Compare values of CVP, Δpp, HR and MAP as predictors of blood volume after supply of 500 ml of 0.9% saline solution.

Interventions

comparing values obtained before and after administration of 500 ml of 0.9% salin

Sponsors

Federal University of Uberlandia
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Being in circulatory shock and have at least one of the following criteria to identify loss of tissue perfusion: systolic blood pressure \<90 mmHg or need for vasoactive drugs, urine output below 0.5 ml / kg / h. * Being under sedation, assessed by the scale of Richmond agitation and sedation (RASS) -5, mechanically ventilated in volume control mode with tidal volume between 8 to 12 ml/kg, PEEP to 8 cm H2O. * Tue signing the informed consent by legal guardian.

Exclusion criteria

* Presence cardiac arrhythmias. * Presence of abdominal or thoracic trauma. * Contraindication for passive elevation of the members. * Hypoxia significant PaO2/FiO2 \< or equal 100.

Design outcomes

Primary

MeasureTime frame
Different Backrest position's effect on CVP, CO and ∆PP measuresData collection was performed at admission or within 10 days of hospitalization between September 2013 and February 2014.

Countries

Brazil

Contacts

Primary ContactRosangela O Felice, Expert
rosangelafelice@gmail.com+553432182258

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026