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Cord Milking and Activity Of The Immune System In Preterm Infants

Cord Milking and Activity Of The Immune System In Preterm Infants

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02043249
Enrollment
200
Registered
2014-01-23
Start date
2014-01-31
Completion date
2016-01-31
Last updated
2014-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm Delivery

Keywords

DELAYED CORD CLAMPING, MILKING OF CORD, PREMATURE INFANTS, LEVEL OF IgG IN NEONATES

Brief summary

In the embry life there is a passage of IgG type, from the mother to tha embryoyo and only in the age of 3-5 month after birth the infant start to develop them by himself. In preterm infants the starting point of the level of the IgG's is lower from the level of term infants. Delayed cord clamping /milking it was prooved in many researches as benificial in terms of : levels of hemoglobin; hematocrit and feritin in the neonats. Also benefits were proved by means of less need for blood tranfusion, less intra ventricular hemorrhage; necrotzing entero colitis and iron deficiency anemia. The hypothesis is that delayed clamping /milking it will increse the level of IgG's in preterm infants. The end point hypothesis is that delayed cord clamping /milking cause to less fever disease or hospitalization it the neonats.

Detailed description

In this study we come to a prove that if we miking the cord in preterm infats we will increse the level of IgG .

Interventions

MILKING OF UMBILICAL CORD OF THE BABY

Sponsors

Hillel Yaffe Medical Center
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
24 Weeks to 37 Weeks
Healthy volunteers
Yes

Inclusion criteria

* PRETERM INFANS BETWEEN 24+0/7 TO 36 * 6/7 WEEKS. * NEWBORN FOR MOTHER WHO AGREE TO PARTICIPATE IN THE RESEARCH WHO DELIVER IN NORMAL DELIVERY / PLANED OR URGENT CESARIAN DELIVERY

Exclusion criteria

* INTRA UTERINE GROWTH RESTRICTION, INFANT UNDER 10% TO AGE OF PREGNANCY. * MOTHER WHO IS NOT WILLING TO PARTICIPATE IN RESEARCH. * NEONATES TO MOTHER WHOM SUSPECTED TO BE IMMUNO- COMPROMISED OR HAVING INFECTION AROUND DELIVERY.

Design outcomes

Primary

MeasureTime frameDescription
levels of IgG in preterm infats24 hours after delivery and after 24 hours..Blood test for IgG's level from the baby in : at delivery . 24 hours after delivery. before discharg from hospital

Secondary

MeasureTime frameDescription
Mother's telephone questioning about the infant disease: fiver / hospitalization/tretment wit antibiotic.3 and 6 month after deliveryPhone call interview of the mother in 3 and 6 month from delivery about : emergengy room admission; hospitalization, fever disease and antibiotic treatment in this time period.

Countries

Israel

Contacts

Primary ContactRIVKA FRANKEL, M.D
RIVKA.LUTVACK@GMAIL.COM972-528721581
Backup ContactESTER PRI-OR
ESTERP@HY.HEALTH.CO.IL972-506629699

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026