Preemptive Analgesia With Morphine Sulphate in Major Urological Surgery

Influence of Premedication With Oral Morphine Sulphate on Analgesic Consumption in Patient Undergoing Major Urological Surgery. Comparison Between Two Different Doses

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02041988

Enrollment

Registered

2014-01-22

Start date

2013-02-28

Completion date

2014-07-31

Last updated

2014-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

premedication, oral morphine, preemptive analgesia

Brief summary

In this study safety and efficacy of oral morphine sulphate is evaluated in order to reduce opioids administration during major urological surgery

Detailed description

The administration of oral morphine sulfate could be useful to reduce the use of opioids in major urological surgery. This study aims to assess the safety and efficacy of two different oral morphine sulphate doses 0,2 mg/kg vs 0,4mg/kg in major urological surgery.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

American Society of Anaesthesiologists physical status classification I/ II, age between 18 - 75, BMI 18 -30

Exclusion criteria

American Society of Anaesthesiologists physical status classification III/ IV, renal and hepatic insufficiency, postoperative nausea and vomiting after oral opioids administrations, neurological and psychiatric disorders.

Design outcomes

Primary

Measure	Time frame
morphine sulphate consumption	six months

Secondary

Measure	Time frame
vital signs	six months

Other

Measure	Time frame
VAS score	six months
side effects	six months

Countries

Italy

Contacts

Primary ContactFrancesco FC Cannata, MD

francesco.cannata@uniroma1.it+390649970283

Outcome results