Reduction of Peroperative Blood Loss During Liver Resection
Conditions
Keywords
Liver surgery, Blood loss, CUSA, Hepatic transection
Brief summary
Intrahepatic division of the hepatic vein is associated with less blood loss than extrahepatic dissection and division of the right hepatic vein.
Interventions
PROCEDUREIntrahepatic division of the right hepatic vein.
Ligation and division of the entrance of the right hepatic vein into the suprarenal cava vein are done at the end of transection of the liver parenchyma with CUSA.
PROCEDUREExtrahepatic vein division
Standard surgical procedure with extrahepatic ligation/division of the right hepatic vein prior to parenchymal division with CUSA.
Sponsors
Jansson, Anders, M.D.
Bengt Isaksson
Karolinska University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Hepatic lesion amenable to right sided hemihepatectomy.
Exclusion criteria
* Hepatic lesions not suitable for a anatomical right sided hemihepatectomy. * Unfit for surgery * Unwillingness to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative bloodloss | Intraoperative time (in minutes) for the division of the liver parenchyma |
Secondary
| Measure | Time frame |
|---|---|
| Operation time, postoperative complication rate | Total time in minutes spent in theater, in hospital stay in days (on an average less than 30 days), total complication rate during hospital stay (on an average less than 30 days), surgical complications during in hospital stay (on an average<30days). |
| postoperative complication rate | in hospital stay in days (on an average <30 days), total complication rate during hospital stay (on an average <30 days), surgical complications during in hospital stay (on an average <30 days). |
Countries
Sweden
Outcome results
None listed