Sleep Disordered Breathing in Children: Inflammation and Oxidative Stress

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02040701

Enrollment

300

Registered

2014-01-20

Start date

2006-05-31

Completion date

Unknown

Last updated

2014-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endothelial Dysfunction, Sleep Disordered Breathing (SDB)

Brief summary

The purpose of the study is to measure markers of inflammatory and oxidative stress known to be associated with cardiovascular morbidity in snoring children. In addition, to measure markers of local inflammation and to evaluate the response to treatment.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

6 Months to 18 Years

Healthy volunteers

Yes

Inclusion criteria

* children ages 6 months-18 years * suspected sleep-disordered breathing or will attend the pre-operative ENT clinic for adenoidectomy or adenotonsillectomy

Exclusion criteria

* craniofacial abnormalities * neurological disorders * genetic disorders * infectious disease * chronic inflammatory disease * any underlying chronic medical condition

Design outcomes

Primary

Measure	Time frame	Description
Plasma inflammatory-markers	After the blood analyzed	Sleep disordered breathing (SDB) in children is associated with increased markers of inflammation, atherogenesis and oxidative stress.

Countries

Israel

Contacts

Primary ContactRiva Tauman, Dr.

tauman@tlvmc.gov.il

Outcome results