The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue

Status

Completed

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02038595

Enrollment

Registered

2014-01-16

Start date

2012-09-30

Completion date

2013-12-31

Last updated

2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brown Adipose Tissue

Keywords

brown adipose tissue

Brief summary

This study seeks to assess a novel imaging technique to image brown adipose tissue utilizing the norepinephrine transporter.

Interventions

RADIATIONPET imaging

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* age 18-30 yrs * BMI \< 24 kg/m2 * Caucasian

Exclusion criteria

* Current neuro-psychiatric illness * substance abuse * medical or neurological illnesses likely to affect physiology or anatomy, i.e., uncontrolled hypertension, cardiovascular disorders * current pregnancy * current breast feeding * suicidal ideation or behavior * use of medications which potentially affect NET binding within 2 weeks of the PET scans.

Design outcomes

Primary

Measure	Time frame
detection of brown adipose tissue based on PET imaging	1 year

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026