Renal Failure
Conditions
Keywords
caudal, epidural, pediatric, renal, transplant, hemodynamics
Brief summary
pain control in pediatric renal transplant is a major concern. the main goal during anesthesia of renal transplant in pediatrics is to maintain hemodynamics in a range close to that of the adult donor. epidural analgesia is thought to be very effective in pain control. this study emphasises the ease of application of epidural catheter via the caudal route to the lower thoracic level; avoiding possible complications that may arise from lumbar or thoracic routes, and its effects on hemodynamics when using analgesic doses of local anesthetics and narcotics.
Interventions
DEVICEB-Braun, Perifix® ONE Paed, Germany
caudal epidural catheterization bupivacaine fentanyl
DRUGPethidine
pethidine intravenous at a dose 1mg/kg when pain score more than 5 postoperative rescue analgesia
DRUGPropofol
fentanyl propofol atracurium besylate
DRUGBupivacaine
DRUGFentanyl
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
3 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* 3-12 years * end stage renal disease * no known allergy to bupivacaine * both sexes
Exclusion criteria
* known allergy to bupivacaine * inflammation at caudal area * spinal cord deformity
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraoperative blood pressure | from the induction of anesthesia till end of surgery at half an hour intervals | measure systolic and diastolic blood pressure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| postoperative heart rate | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours | — |
| postoperative central venous pressure | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours | — |
| intraoperative central venous pressure | fromom the induction of anesthesia till end of surgery at half an hour intervals | — |
| intraoperative heart rate | from the induction of anesthesia till end of surgery at half an hour intervals | — |
| postoperative blood pressure | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours | record systolic and diastolic blood pressure every hour for the first 24 hours postoperative |
Other
| Measure | Time frame |
|---|---|
| pain scoring system (objective behavioural pain score) | from the time of transfere to the nephrology ICU, every hour for the first 24 hours postoperative |
Countries
Egypt
Outcome results
None listed