Comparison of a Bilateral TAP Block and Preperitoneal Instillation of Local Anesthetic for a Total Extraperitoneal (TEP) Repair

Comparison of an Ultrasound Guided Bilateral Transversus Abdominis Plane Block With Dexamethasone and Preperitoneal Instillation of Local Anesthetic With Dexamethasone to a Standard Anesthetic Technique for Analgesic Efficacy and Patient Satisfaction Following a Total Extraperitoneal Bilateral Inguinal Hernia Repair: A Prospective Randomized Single Blinded Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02036983

Enrollment

Registered

2014-01-15

Start date

2013-11-30

Completion date

2015-08-31

Last updated

2018-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bilateral Inguinal Hernia Repair

Keywords

Ultrasound guided, Bilateral Transversus abdominis Plane Block, Dexamethasone, Preperitoneal Instillation, Local Analgesic, Efficacy, Total Extraperitoneal Bilateral Inguinal hernia repair

Brief summary

Comparison of an ultrasound guided bilateral TAP (transversus abdominis plane) block with dexamethasone and preperitoneal instillation of local anesthetic with dexamethasone under direct visualization will be compared it to a standard anesthetic technique (control) following a TEP (total extraperitoneal) bilateral hernia repair. The investigators are hypothesizing that the bilateral TAP block and preperitoneal instillation of local anesthetics with the addition of dexamethasone are superior in terms of patient satisfaction and post-operative pain control when compared to a standard anesthetic technique (no regional technique).

Interventions

PROCEDURETransversus abdominis plane block (TAP BLOCK)

Ultrasound guided TAP block with local anesthetics and dexamethasone.

PROCEDUREInstillation of surgical site with local anesthetic.

Instillation of surgical site with local anesthetics and dexamethasone.

PROCEDUREOpioid IV medications (Control)

Standard anesthetic technique.

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* 18-80 yrs of age * American Society of Anesthesiologists (ASA) physical status 1-3 * Scheduled for outpatient TEP bilateral inguinal hernia repair

Exclusion criteria

* Patients refusal to participate * inability to give consent * drug allergies to medications used in study * pregnancy * bleeding diathesis * conversion to an open procedure * any subject whose anatomy, or surgical procedure, in the opinion of the investigator might preclude the potential successful performance of a TAP block * any subject whose anatomy, or surgical procedure, in the opinion of the investigator, might preclude the potential successful performance of a TAP block

Design outcomes

Primary

Measure	Time frame	Description
Assess the efficacy of a bilateral TAP block and preperitoneal instillation of local anesthetic to a standard anesthetic technique for TEP hernia repair	Post-operatively (Day 1)	Assessment will be done postoperatively using a Quality of Recovery 40 (QoR-40) questionnaire after surgery.

Secondary

Measure	Time frame	Description
Assess the efficacy of a bilateral TAP block and preperitoneal instillation of local anesthetic to a standard anesthetic technique for TEP hernia repair	Post-operatively (Day 0 to 1)	Total opioid use in the post anesthesia care unit (PACU) and the period following surgery.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 1, 2026