Central Serous Retinopathy (CSR)
Conditions
Brief summary
First, this study will investigate the viability of 24-hour eye patching as a potential treatment modality for CSR. Second, this study will assess a potential physiologic explanation for CSR, namely if inhibition of photic stimulation of the diseased retina will aid in ameliorating disease severity and disease duration.
Interventions
DEVICEEye Patching
Sponsors
Washington University School of Medicine
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults 18 years of age and older * Both males and females * Patients diagnosed with active central serous retinopathy * Patients who are willing to use an eye patch in the affected eye for 24 hours * Patients who are able to make the follow up appointments as required by the study
Exclusion criteria
* Individuals under 18 years of age * Patients with vision less than 20/40 in the unaffected eye. * Patients who are not able to undergo mfERG testing in a realiable manner.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in multi-focal ERG response and macular thickness after 24-hour patch therapy in patients with CSR | 24 hours | This study is a prospective control trial that will compare 24-hour eye patch therapy with the current standard of care in patients with central serous retinopathy (CSR). |
| Change in multi-focal ERG response | 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| macular thickness | 24 hours |
Countries
United States
Outcome results
None listed