Cognition Disorders, Psychiatric Diagnosis
Conditions
Keywords
Psychiatric morbidity, Cognitive function, Heart transplantation, Mortality, Cardiac allograft vasculopathy
Brief summary
The investigators aim at characterizing neuropsychiatric consequences of heart transplantation (HTX) and at assessing the impact of depressive symptoms after HTX on mortality and cardiac allograft vasculopathy (CAV).
Interventions
None listed
Sponsors
Oslo University Hospital
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Participant in one of two former studies and heart transplanted at the time of inclusion into this former study
Exclusion criteria
* Cognitively not capable to consent to participation and/or * Insufficient fluent in the Norwegian language to complete both psychiatric and neuropsychological assessment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Psychiatric morbidity | At time of enrollment | Psychiatric diagnoses by clinician and self-rapport |
| Cognitive function | At time of enrollment | Neuropsychological assessment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| All cause mortality | 14 and 3 years respectively | Time since enrollment in former study; i.e. approximately 14 years (study 1) and approximately 3 years (study 2) |
| Cardiac allograft vasculopathy | 14 and 3 years respectively | Time since enrollment in former study; i.e. approximately 14 years (study 1) and approximately 3 years (study 2) |
Other
| Measure | Time frame | Description |
|---|---|---|
| Cerebral pathology | At time of enrollment | MRI of the brain |
Countries
Norway
Outcome results
None listed