Chronic Obstructive Pulmonary Disease, Patients Hospitalized for a COPD Exacerbation
Conditions
Keywords
COPD Exacerbation, Pulmonary embolism, Standardized and consensus diagnostic strategy
Brief summary
A standardized diagnostic strategy of pulmonary embolism will be applied to eligible patients, incorporating a clinical probability score (revised Geneva score), plasma D-dimer assay and if necessary, a multidetector-row CT angiography thoracic and venous ultrasound of the lower limbs. All the patient with a pulmonary embolism diagnosed or not, will be followed for 3 months.
Interventions
OTHERPEP
Sponsors
University Hospital, Brest
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients hospitalized for a COPD exacerbation * COPD previously diagnosed
Exclusion criteria
* Allergy to iodinated contrast * Creatinine clearance \< 30 mL / min * Patient hospitalized for exacerbation of COPD for more than 48 hours * Pneumothorax * Exams impossible to be performed * Pregnancy * Life expectancy \< 3 months * Patients already receiving anticoagulant therapy for another reason (mechanical valve, cardiac arrhythmia).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of pulmonary embolism in patients hospitalized for a clinical exacerbation of COPD. | 27 months |
Secondary
| Measure | Time frame |
|---|---|
| The rate of pulmonary embolism diagnosed during the 3 month follow-up in patients whom pulmonary embolism was initially excluded when they've been included in the study | 27 months |
Countries
France
Outcome results
None listed