Intravesical Instillation of Hyaluronic Acid to Decrease Incidence of Urinary Tract Infection

Is Intra - Neobladder Installations of Hyaluronic Acid, Effective in Reducing Neobladder Orthotropic Reconstruction Post-operative Urinary Tract Infections?

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02034890

Enrollment

Registered

2014-01-14

Start date

2015-07-31

Completion date

Unknown

Last updated

2019-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary Tract Infection

Keywords

orthotopic neobladder, urinary tract infection, intravesical instillation, hyaluronic acid

Brief summary

Prospective trial which includes instillation of intravesical hyaluronic acid in an attempt to reduce the incidence of urinary tract infections in patients after orthotopic neobladder reconstruction.

Interventions

DRUGHyaluronic Acid

intravesical instillation of 40 mg of hyaluronic acid in 6 specific time points: 1,2,3 and 4 weeks postoperatively (After radical cystectomy and orthotopic neobladder reconstruction) 2 and 3 months postoperatively

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients undergoing radical cystectomy and orthotopic neobladder reconstruction

Exclusion criteria

* patients \<18 years and unwilling to participate in this study

Design outcomes

Primary

Measure	Time frame
positive urinary culture	6 months

Secondary

Measure	Time frame
urinary tract infection	6 months

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026