Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy

A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Femoral Nerve Block for Analgesia Post Total Knee Arthroplasty

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02033603

Enrollment

Registered

2014-01-13

Start date

2014-01-31

Completion date

2014-12-31

Last updated

2015-01-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

Total knee arthroplasty, Total knee replacement, Femoral Nerve Block, Adductor Canal Block

Brief summary

Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages. It is a painful surgery and one of the methods to reduce post-operative pain is performing a regional anaesthesia technique. The current practice is to perform a femoral nerve block (FNB) which blocks the nerves supplying the knee joint and the thigh muscles (quadriceps). This provides effective analgesia. However, it also results in weakness of the quadriceps and may result in falls post-operatively. Adductor canal block (ACB) is a new, alternative regional anaesthesia technique which is hypothesised to provide as effective analgesia, with less quadriceps weakness compared to FNB, hence potentially reducing the risk of falls post-operatively. Investigators aim to study if the analgesia provided by ACB is as good as FNB while preserving quadriceps strength.

Interventions

DRUGRopivacaine

30mls of 0.5% ropivacaine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

45 Years to 85 Years

Healthy volunteers

Inclusion criteria

* ages 45-85 * American Society of Anaesthesiologists physical status 1-3 * BMI 18-35 kg/m2

Exclusion criteria

* inability to give consent, communicate, cooperate * Patients with regular consumption of strong opioids (morphine, oxycodone) or steroids * Patients with allergy to local anaesthetics or any drugs included in the study * Patients with lower limb surgery in the preceding year * Patients with pre-existing neurological deficits * Patients who are unsuitable for general anaesthetics (eg difficult airway)

Design outcomes

Primary

Measure	Time frame
Morphine consumption	first 24 hours

Secondary

Measure	Time frame
Pain scores	1, 6, 12, 24, 48
Morphine consumption	48 hours
Side effects of opioids- sedation, nausea and vomiting	48 hours
Quadriceps strength, ability to mobilise	24, 48 hours

Countries

Singapore

Contacts

Primary ContactCTRU CGH

67888833

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026