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The Feasibility of PetCO2 Prediction Hypotension Under Spinal Anesthesia for Cesarean Section

The Feasibility of PetCO2 Prediction Hypotension Under Spinal Anesthesia for Cesarean Section

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02032355
Enrollment
6
Registered
2014-01-10
Start date
2014-01-31
Completion date
2014-02-28
Last updated
2014-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carbon Dioxide, Hypotension

Brief summary

Maternal hypotension is a common side effect after spinal anesthesia for cesarean delivery.Decreased vascular resistance and cardiac output, due to sympathetic blockade1and blood pooling in blocked areas of the body respectively, are main causes of spinal anaesthesia-induced hypotension during Caesarean delivery. Cardiac output, which has shown to be a better predictor of organ and placental perfusion than arterial blood pressure.Few studies have measured CO after spinal anesthesia in the maternal population.This is largely because of the lack of availability of accurate and reproducible noninvasive measurement techniques. Up to now, preventing hypotension has continued to focus on arterial blood pressure variables, fluid, and ephedrine requirements as markers of cardiovascular status, because these are more easily measured. Investgators hypothesized that CO and PetCO2, in parturients with the degree of hypotension during spinal anaesthesia, would also have a positive and significant association.

Interventions

PROCEDUREspinal anesthesia

Sponsors

Geng guiqi
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* full-term gestation (\>36 and \<41 weeks of gestation) with a singleton pregnancy

Exclusion criteria

* emergency cases * placenta praevia * preeclampsia * cardiovascular or cerebrovascular disease * morbid obesity with a BMI≥40 * contraindications to spinal anaesthesia

Design outcomes

Primary

MeasureTime frame
value of PetCO2 and changes in artery pressureup to 4 weeks

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026