Prospective Observational Correlation of Sperm Assay Results With Blastocyst Formation

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02031549

Enrollment

Registered

2014-01-09

Start date

2014-01-31

Completion date

2014-04-30

Last updated

2015-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

We will investigate potential correlation between SpermComet DNA fragmentation assay results and IVF cycle outcome.

Detailed description

A SpermComet assay will be used to characterize DNA fragmentation of surplus sperm samples remaining after in vitro fertilization (IVF) cycles. We will investigate potential correlation between these assay results and the outcomes of IVF cycles that used those sperm samples.

Interventions

OTHERSpermComet assay

Measurement of DNA fragmentation in samples of surplus sperm (diagnostic, not an intervention).

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Undergoing IVF * Surplus sperm available after oocyte insemination * Consented

Exclusion criteria

* Surgical sperm extraction * Use of donated sperm or oocytes * No minors may participate

Design outcomes

Primary

Measure	Time frame	Description
Blastulation rate	6 days	The proportion of oocytes and of fertilized oocytes that form blastocysts.

Secondary

Measure	Time frame	Description
Fertilization rate	1 day	Proportion of inseminated oocytes that form exactly two pronuclei.
Embryo grade	6 days	Grade and measurements of blastocysts that form.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026