CCTA-based Coronary Plaque Characterization and High-sensitive Troponin T for the Prediction of Cardiovascular Outcomes

Comprehensive 'Bio-Imaging' Using Quantitative Coronary Plaque Composition Assessment and the High-sensitive Troponin T for the Prediction of Cardiac Outcomes.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02030704

Enrollment

300

Registered

2014-01-08

Start date

2008-02-29

Completion date

2018-09-30

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease, Noninvasive Plaque Characterization

Brief summary

To determine the ability of semi-automated plaque assessment in cardiac computed tomography angiography (CCTA) and high sensitive troponin T (hsTnT) for the risk stratification of patients at intermediate risk for coronary artery disease (CAD).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Clinical indication for CCTA according to the current appropriate use criteria

Exclusion criteria

* non-sinus rhythm * acute coronary syndromes * cardiomyopathies * moderate or severe valvular disease * elevated serum creatinine (\>1.5 mg/dl) * history or ECG signs of previous myocardial infarction * severe iodine allergy.

Design outcomes

Primary

Measure	Time frame
Cardiac death	two years
Nonfatal myocardial infarction	two years

Secondary

Measure	Time frame	Description
Myocardial revascularization including PCI and CABG	two years	PCI - Percutaneous Coronary Intervention CABG - Coronary Artery Bypass Grafting

Countries

Germany, Hungary

Outcome results