Proteomics in Multiple Trauma to Identify Organ Failure

Analysis of Predictive Parameters by Proteomics for Early Diagnosis of Organ Dysfunction in Multiple Trauma Patients - A Pilot Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02030327

Enrollment

Registered

2014-01-08

Start date

2014-01-31

Completion date

2022-12-31

Last updated

2022-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Trauma

Keywords

proteomics, multiple trauma, organ dysfunction

Brief summary

To analyse differences in protein expression in multiple trauma patients for identification of potential biomarkers to predict organ dysfunction.

Detailed description

The aim of the present study in humans is to analyse differences in protein expression after multiple trauma in patients for identification of potential biomarkers to predict organ dysfunction.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* older than 18 years * multiple trauma patients * ISS \>16

Exclusion criteria

* children * ISS \<16

Design outcomes

Primary

Measure	Time frame	Description
Number of patients with disease or death vs. healthy	Day 0 until day 20	Starting at day O, then every 24 hours until day 20

Countries

Germany

Outcome results