Abdominal Wall Muscles, Inguinal Hernia, Postoperative Pain, Regional Anesthesia
Conditions
Keywords
transversus abdominis plane block, inguinal hernia repair, acute postoperative pain, neuropathic pain
Brief summary
This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients undergoing unilateral inguinal hernia repair with a mesh under general anaesthesia, and how the efficiency of early postoperative analgesia achieved correlates with the risk of developing a chronic pain state, a not uncommon condition after this type of surgery.
Interventions
PROCEDURETransversus abdominis plane block
ultrasound guided transversus abdominis plane block
Sponsors
Papacharalampous Panagiota
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
ASA I-III patients undergoing inguinal hernia repair with a mesh age between 18 and 75 years old ability to read and write greek \-
Exclusion criteria
* Inability to consent to the study * BMI \>40kg/m2 * Skin infection at the puncture site * Contraindication to mono-amide local anaesthetics, paracetamol, NSAID's (parecoxib) * Preoperative use of opioids or NSAID's for chronic pain conditions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain scores at rest and with movement using the numerical rating scale (NRS) | 3, 6 and 24 hours postoperatively |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of chronic pain | 6 months after surgery |
Other
| Measure | Time frame |
|---|---|
| Morphine consumption (mg) | 24 hours postoperatively |
Countries
Greece
Outcome results
None listed