Ischemic Stroke, Sleep Apnea Syndrome
Conditions
Keywords
stroke, SAHS, BiPAP
Brief summary
Ischemic stroke is a kind of common disease with great harm. In acute stage of stroke there is sharply increasing morbidity of sleep apnea hypopnea syndrome. Our suppose that treatment with noninvasive ventilation for patients with acute ischemic stroke should improve the functional prognosis（measuring with 90d modified Rankin score）.
Detailed description
In acute state of ischemic stroke，if patients with sleep apnea hypopnea syndrome may need additional respiratory management such bi-level positive airway pressure.We supposed the patients with stroke can take benefit of functional recovery form bi-level positive airway pressure. We choose the patients who suffered ischemic stroke in 48 hours ，then evaluate the respiratory status. Stroke patients who were diagnosed as sleep apnea hypopnea syndrome will accept additional treatment with bi-level positive airway pressure for 7 night（per night 6 hours）.Then the modified Rankin scale score and NIHSS will be recorded at 30 days and 90 days after stroke.
Interventions
DEVICEBi level positive pressure ventilation
Bi level positive pressure ventilation should be given for subject for 6 hours per night ，total 7 times.
Sponsors
Peking University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
35 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* ischeic stroke onset within 48 hours , NIHSS:4-15
Exclusion criteria
* mRs\>2 before onset of enrollment severe hepatic renal insufficiency cancer in reached an advanced stage
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Modified Rankin Scale score | 90 days after symptoms | 0-2 Modified Rankin Scale score should be recognized good functional prognosis |
Countries
China
Outcome results
None listed