Cardiovascular Diseases
Conditions
Brief summary
This prospective cohort study of an almond-enriched diet (within the overall context of Asian Indian dietary guidelines) was conducted to test the hypothesis that in patients with T2DM almond-enriched balanced diet improves glycemic measures and CVD risk factors.
Interventions
DIETARY_SUPPLEMENTalmond
Sponsors
Diabetes Foundation, India
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
25 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients in the age range of 25-65 years * on stable doses of metformin from past 3 months * having HbA1C less than 9% * LDL-c ≥100 mg/dl were recruited
Exclusion criteria
* Patients on insulin therapy, plioglitazone, insulin secretagogues, beta blockers or steroids or suffering from diabetes for more than 10 years * having high uric acid levels (≥ 8 mg/dl), * with accelerated hypertension (stage 2 hypertension according to JNC guidelines) , hypothyroidism, suffering from acute infection or any debilitating disease or with renal failure, * appreciable weight loss (more than 10%) during past 6 months * Patients with known food allergy, lipid altering medication or extraneous factors that can affect glycemic or lipid parameters
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in LDL-c | baseline, after six months |
Secondary
| Measure | Time frame |
|---|---|
| HbA1C | baseline, after six months of intervention |
Countries
India
Outcome results
None listed