Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus

Phase 4 Study of Comparison of Postoperative Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus Blockade for Arthroscopic Shoulder Surgery

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02026050

Enrollment

Registered

2014-01-01

Start date

2014-01-31

Completion date

2015-01-31

Last updated

2015-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

dexamethasone, intraarticular injection, interscalene brachial plexus block

Brief summary

the aim of this study was to investigate the analgesic efficacy of intra articular dexamethasone administration for arthroscopic shoulder surgery.

Detailed description

shoulder surgery can be very painful and interscalene brachial plexus block is the gold standard in the management of acute pain after shoulder surgery. various local anaesthetic mixtures can be used to prolong local anaesthesia duration and epinephrine , opioids and dexamethasone are frequently used for this purpose. dexamethasone has also been found the prolong the duration of lidocaine axillary blocks and intravenous regional anaesthesia. intraarticular administration of medicines can be used for management of joint pain and opioids , local anaesthetics and dexamethasone are used for this purpose.In addition, there are no studies available to compare the different treatment methods used in clinical practice directly.

Interventions

PROCEDUREintraarticular dexamethasone

2ml 8 mg dexamethasone administration for intraarticular

PROCEDUREinterscalene dexamethasone

2ml 8 mg dexamethasone administration interscalene brachial plexus added 30 ml 0.5 % bupivacaine

PROCEDUREserum phsyologic

interscalene brachial plexus block was preoperative performed 30 ml 0.5 % bupivacaine+ 2ml serum phsyologic and after surgery 10 ml serum phsyologic administration for intraarticular

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* between 18-65 years * arthroscopic shoulder surgery * no known allergies to drugs * ASA 1-2 patients

Exclusion criteria

* history of diabetes * history of chronic pain treatment * pregnancy * severe bronchopulmonary disease * systemic glucocorticoid use

Design outcomes

Primary

Measure	Time frame	Description
analgesic consumption	postoperative 1 day	morphine consumption (patient controlled analgesia procedure) was recorded

Secondary

Measure	Time frame	Description
visual analog scale	postoperative 1 day	Visual analog scale on rest and movement was recorded

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026