Healthy, Overweight or Obese Adults
Conditions
Brief summary
It has previously been observed that increased fish intake improves the metabolic health of overweight and obese adults, and animal protein improved metabolic health of obese rats. In this project the investigators will investigate whether increased intake of fish or meat improves metabolic health in overweight/obese adults aged 20-55 years when replacing processed food. The hypothesis is that increased intake of unprocessed fish or meat will improve metabolic health in adults as measured by glucose tolerance, lipid metabolism and inflammatory markers.
Interventions
Sponsors
The Fisheries and Aquaculture Industry Research Fund
University of Bergen
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI \> 27 * 20-55 years * healthy
Exclusion criteria
* diagnosed diseases such as diabetes, CVD, intestinal diseases, arthritis * prescription medications affecting the metabolism of glucose, lipids or the immune system * use of supplements containing long chain n-3 fatty acids * high intake of fish * food allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in metabolic status (glucose, lipids, inflammation) | Baseline and end of intervention (12 weeks) | The effects of fish intake on glucose homeostasis, lipid metabolism and inflammation will be assessed. |
Secondary
| Measure | Time frame |
|---|---|
| Changes in plasma concentrations of amino acids and their metabolites | Baseline and end of intervention (12 weeks) |
| Changes in plasma concentrations of vitamins | Baseline and end of intervention (12 weeks) |
Countries
Norway
Outcome results
None listed