Adenocarcinoma of Prostate
Conditions
Keywords
prostate biopsy, local anesthesia, cancer detection rate.
Brief summary
Transrectal ultrasound guided prostate biopsy (TRUS-Bx) is the gold standard method for prostat cancer diagnosis. Cancer detection rate is an important issue in TRUS-Bx. Effective biopsy protocol is necessary to enhance cancer detection rate during the procedure. Patient tolerance may improve the protocol effectiveness and quality. Adequate patient tolerance with optimal local anesthesia may enhance cancer detection rate in TRUS-Bx.
Detailed description
In transrectal ultrasound guided prostate biopsy ultrasound's probe manipulation is necessary for effective biopsy. Patient discomfort and pain frequently occurs with manipulation of probe during transrectal ultrasound guided prostate biopsy and this situation may qualify of the achievement of this procedure. In this study, we aimed to describe the impact of different two local anesthesia types on cancer detection rate in transrectal ultrasound guided prostate biopsy.
Interventions
DRUGintrarectal lidocaine gel
intrarectal local anesthetic application
DRUGperiprostatic nerve blockade
periprostatic local anesthetic application
Sponsors
Bagcilar Training and Research Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
MALE
Healthy volunteers
No
Inclusion criteria
* Patients who underwent transrectal ultrasound guided prostate biopsy because of elevated serum PSA levels and/or suspicious rectal examination of prostate.
Exclusion criteria
* Previous TRUS-Bx and prostatic operations(TUR-P, open prostatectomy, etc..) history, treatment for prostate carcinoma, usage of finasteride and dutasteride.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cancer detection rate with anesthesia type | finally pathologic evaluation within 2-3 weeks |
Countries
Turkey (Türkiye)
Outcome results
None listed