Coronary Artery Disease
Conditions
Keywords
coronary artery disease, elderly, exercise, exercise-based cardiac rehabilitation
Brief summary
The purpose of this study is to investigate the effects of exercise for patients with coronary artery disease (CAD) aged 80 years and older, with special reference to maximum aerobic capacity, muscle endurance, physical functioning, level of physical activity, health related quality of life, anxiety, depression and endothelial function, compared to a control group.
Interventions
OTHERExercise
Individually prescribed hospital based exercise in group two times a week, home-based exercise once a week. The exercise intervention consists of interval based aerobic exercise on a bicycle ergometer 30 minutes with intensity level at 13-17 at Borg scale, resistance exercises and balance exercises
Sponsors
Sahlgrenska University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
80 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of acute coronary artery disease * Aged 80 years or older
Exclusion criteria
* Inability to understand or speak the Swedish language * Serious physical or psychological disease interfering with participation in an exercise intervention * Patients are already exercising three times or more/week
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in maximum aerobic capacity | At baseline and after 4 months | A maximum exercise test on an electronically braked cycle ergometer, with watts as marker of maximum aerobic capacity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in level of physical activity | At baseline and after 4 months | Level of physical activity will be measured by an accelerometer and an activity diary |
| Change in muscular endurance | At baseline and after 4 months | Will be measured by three clinical endurance tests including unilateral isotonic heel lift, unilateral isotonic shoulder flexion, bilateral isometric shoulder abduction |
| Change in physical functioning | At baseline and after 4 months | Including tests of balance: short physical performance battery, one leg standing, timed up and go, and the activities specific balance confidence scale. |
| Change in transthoracic evaluation of resting coronary flow velocity | At baseline and after 4 months | — |
| Change in anxiety and depression | At baseline and after 4 months | measured by the hospital anxiety and depression scale |
| Change in endothelial function | At baseline and after 4 months | Evaluated with non-invasive ultrasound |
| Change in health related quality of life | At baselline and after 4 months | measured by a self-rated health questionnaire |
Countries
Sweden
Outcome results
None listed