Pain
Conditions
Keywords
Pain, abortion, paracetamol, lornoxicam
Brief summary
To compare between the efficacy of Paracetamol IV vs. Lornoxicam IV in pain relief following surgical abortion. The medication will be given at the time of the procedure. Following the abortion, pain level will be evaluated.
Detailed description
Patients with medical indication for surgical abortion during first trimester will be divided to two groups. The study groups, the surgeons and the nurses will be blinded to one of the treatment arms. Pain will be evaluated at fixed intervals following the abortion. Comparison in pain levels between the study groups will be analysed.
Interventions
DRUGParacetamol
Pain treatment with aniline analgesics (paracetamol) at the time of the procedure
DRUGlornoxicam
Pain treatment with NSAID (lornoxicam) at the time of the procedure
Sponsors
Rambam Health Care Campus
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Elective surgical abortion for first trimester pregnancy
Exclusion criteria
* Chronic pelvic pain * Fibromyalgia * Pelvic inflammatory disease * Chronic renal failure, liver disease, peptic ulcer * cervical stenosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain | Two hours | Pain level will be evaluated by VAS |
Countries
Israel
Contacts
Primary ContactLior Lowenstein, MD, MS
Outcome results
None listed