Stroke
Conditions
Keywords
stroke, fMRI, DTI
Brief summary
Imaging of the ischaemic penumbra with a particular diffusion-weighted imaging (DWI)/ perfusion-weighted imaging (PWI) mismatch is a promising approach to the selection of patients with acute ischaemic stroke for trials of intervention. The investigators want to apply multimodal resonance imaging methods such as functional magnetic resonance imaging ( fMRI), diffusion tensor imaging (DTI), arterial spin labeling (ASL) to guide treatment and predict the prognosis of stroke.
Interventions
None listed
Sponsors
Zhongda Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
Time from the onset of stroke till hospital within 24 hours. With clinical characteristics such as hemiplegia, headache. Willing and able to comply with the study procedures and provide written informed consent to participate in the study. Patients must understand the nature of the study and give informed consent.
Exclusion criteria
The onset of stroke out of 24 hours. Pregnant women. Patients with intracranial metallic bodies from prior neurosurgical procedure, implanted pacemaker, medication pump, vagal stimulator, deep brain stimulator, TENS unit or ventriculoperitoneal shunt. Past history of seizures within one year or unexplained loss of consciousness. Family history of epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional recovery | Participants will be followed till die or lost to follow-up,an expected average of three year. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Over survival | Participants will be followed till die or lost to follow-up,an expected average of three year | Time from stenting to the day when the patients died or lost to the follow-up |
Countries
China
Contacts
Primary ContactCheng-yu Peng
Outcome results
None listed