Liver Cirrhosis
Conditions
Keywords
liver cirrhosis, liver transplant, nutritional status, bioelectrical impedance vector analysis
Brief summary
Liver transplant is the goal treatment for every patient with end-stage chronic liver disease. Quality of life improves after transplant because the main complications of end-stage liver disease disappear, but due to immunosuppression other alterations appear such as metabolic alterations, weight gain, among others. Body composition and nutritional status can be affected do to post-transplant pharmacologic therapy.
Detailed description
Body composition and nutritional status can be affected due to post-transplant pharmacologic therapy. This is a prospective cohort study, patients from liver transplant waiting list will be assessed, pre and post-transplant measures of body composition and nutritional status will be obtained.
Interventions
None listed
Sponsors
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Liver cirrhosis (any etiology) * Enrolled in waiting list for tliver transplant
Exclusion criteria
* Hepatocellular carcinoma * Chronic renal failure * Congestive cardiac failure * Extremity amputation * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body composition | Baseline, 7 days, 1 month, 3 months and 6 months post-tranpslant | Body composition will be assessed through bioelectrical impedance vector analysis graph. |
Secondary
| Measure | Time frame |
|---|---|
| Liver function tests | Baseline, 7 days, 1 month, 3 months and 6 months post-tranpslant |
Countries
Mexico
Contacts
Primary ContactAldo Torre, MD MSci
Backup ContactAstrid Ruiz-Margain, M.Sci
Outcome results
None listed