Ascites, Liver Cirrhosis
Conditions
Keywords
Paracentesis, Liver Cirrhosis, ascites, body composition
Brief summary
Ascites is a frequent complication of liver cirrhosis, initial treatment consists on diuretics intake, however, as the disease progresses this complication becomes more severe, consequently other therapeutic options are used. Paracentesis is indicated when severe ascites is present and it should be accompanied by albumin infusion. Nutritional status is generally affected in patients with liver cirrhosis, even more patients with severe ascites show decreased energy intake due to gastric compression.
Interventions
BEHAVIORALBody composition in paracentesis
Takin blood samples and bioelectrical impedance measurmeent, Neuropsychological tests evaluation
Sponsors
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Any genre. * Age 18-70 years old. * Diagnosis of liver cirrhosis of any etiology (documented by clinical, biochemical, radiological and / or biopsy. * Presence of high volume ascites * The signing of informed consent will be required for the inclusion of any patient.
Exclusion criteria
* Hepatic encephalopathy grade III or IV. 2) liver transplantation. * Congestive heart failure. * Hemodialysis. * Acute or chronic renal failure. * Nephrotic syndrome with protein loss. * Alcoholism active in the last 6 months. * Pregnancy. * upper gastrointestinal bleeding.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body composition | Baseline and 8 days post treatment | bioelectrical impedance vector analysis |
Countries
Mexico
Contacts
Primary ContactAldo Torre, M.D. M.Sci
Outcome results
None listed