Depression
Conditions
Keywords
Depression, Mood disorder
Brief summary
The primary aim is to prevent depression in youth and parents in a single, integrated family intervention. Hypothesis 1a: Children in the Family Depression Prevention (FDP) program will have significantly lower levels of anxious/depressive symptoms and fewer onsets of depressive episodes as compared to children in the Written Information (WI) condition. Hypothesis 1b: In parents, the amount of time in a depressive episode will be significantly lower for those in the FDP program as compared to those in the WI condition.
Detailed description
Depression is a major public health problem affecting over 15 million U.S. adults annually and is especially prevalent in those of parenting age. Offspring of depressed parents are at increased risk of depression and therefore are a critical target for preventive interventions. The current study aims to reduce the rate of depression in parents and their children by adopting an innovative, family-based approach to simultaneously preventing depression in at-risk youth and in their affected parents. The rationale for this approach is based on (a) a conceptual model that integrates parenting processes, stress (particularly that which is associated with parental depression), and children's self-regulatory skills in the face of stress, (b) evidence that depression runs in families, (c) promising results from family- and child-focused depression prevention programs, (d) evidence that in adults, cognitive-behavioral therapy (CBT) reduces both depressive episodes and their recurrence, and (e) growing consensus among scientists, clinicians, and policymakers on the need for family-based models of healthcare. This 5- year, two-site randomized controlled trial will test a Family Depression Prevention (FDP) program for children (ages 9-15) and their parents with depressive disorders (past or current). This dual prevention approach is a novel synthesis of existing evidence-based intervention techniques drawn from child prevention and adult treatment models. Participating families (N=300) will be randomized to either FDP (10 weekly + 3 monthly sessions) or a written information comparison (WI) condition. All parents and children will be evaluated at pre- and post-intervention, and at 6-, 12-months from baseline.
Interventions
BEHAVIORALFamily Cognitive Behavioral Prevention
Parent training and cognitive behavioral intervention with parents. Coping skills training with children.
BEHAVIORALWritten information
Reading materials about depression
Sponsors
San Diego State University
Vanderbilt University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Masking description
Interviewers who assess diagnostic outcomes are masked to participant condition.
Eligibility
Sex/Gender
ALL
Age
9 Years to 15 Years
Healthy volunteers
No
Inclusion criteria
* Parent with a current or history of a depressive disorder within child's life * Children ages 9- to 15-years-old
Exclusion criteria
* Bipolar I (parent or child) * Schizophrenia (parent or child) * Current alcohol or drug abuse (parent or child) * Conduct disorder; developmental disability (child) * Current diagnosis of a depressive disorder (child)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| In children, the primary outcome is level of symptoms on the Youth Self-report form. | twelve months post baseline | For child participants, we will assess change in their levels of symptoms on the Youth Self-report form at 12-month follow-up. T-scores range from 0 to 100; higher scores indicate more symptoms (i.e., worse outcome). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| In children, level of internalizing and externalizing symptoms on the Child Behavior Checklist completed by parent about the child | 12 months | For child participants, we will assess change in their levels of symptoms on the Child Behavior checklist at 12-month follow-up. |
| Parents: Patient Health Questionnaire - 9 (PHQ-9) | 12 months | Parent participants: The PHQ-9 measures 9 symptoms of depression on a 4-point scale. Scores can range from 0 to 36. |
| Children: depressive diagnoses | 12 months | Children and parents are interviewed about the child's depressive symptoms with the Longitudinal Interval Follow-up Evaluation, which yields scores 1-6 for each week. |
Countries
United States
Outcome results
None listed