Glycemic Response
Conditions
Brief summary
The purpose of this study is to assess whether food ingredient(s) affect glycemic responses.
Interventions
OTHERDietary Intervention
Sponsors
Glycemic Index Laboratories, Inc
PepsiCo Global R&D
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Subject is 18-75 years of age * Subject has a body mass index (BMI) ≥ 20.0 and \< 35 kg/m² at screening (visit 1). * Subject has normal fasting serum glucose (\<7.0mmol/L capillary corresponding to whole blood glucose \<6.3mmol/L). * Subject has no health conditions that would prevent him from fulfilling the study requirements as judged by the Investigator on the basis of medical history. * Subject understands the study procedures and signs forms providing informed consent to participate in the study and authorization for release of relevant protected health information to the study investigator.
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incremental area under the blood glucose response curve | 0-2 hours | Glycemic response calculated from individual glucose measurements upon consumption of control and experimental test food products. The individual glucose measurements will be collected at baseline (prior to consumption of each test food product) and over a 2-hour period following the initiation of consumption of each test food product. The primary outcome is differential treatment-effect on the time-concentration glucose curve over the 2 hours post consumption of each test food product. |
Secondary
| Measure | Time frame |
|---|---|
| Rate of decline in blood glucose, peak blood glucose, peak insulin and adjusted time concentration area for insulin | 0-2 hours |
Countries
Canada
Outcome results
None listed