Active Peptic Ulcer Disease/GI Bleeding
Conditions
Keywords
peptic ulcer bleeding, hemostatic forceps, soft coagulation, argon plasma coagulation
Brief summary
Endoscopic high-frequency soft coagulation is available for the management of bleeding or nonbleeding visible vessels during endoscopic submucosal dissection. However, its efficacy on peptic ulcer bleeding has not been elucidated so far. The aim of this study was to evaluate the efficacy of hemostasis with soft coagulation using hemostatic forceps by comparing it with argon plasma coagulation (APC) in a prospective, randomized trial.
Interventions
DEVICEepinephrine injection plus soft coagulation using hemostatic forceps
DEVICEepinephrine injection plus argon plasma coagulation
Sponsors
Kyunghee University Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age greater than 18 years * peptic ulcer with stigmata of recent hemorrhage
Exclusion criteria
* malignant ulcer * previous gastric surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of bleeding within four weeks after initial hemostasis | up to 24 months |
Secondary
| Measure | Time frame |
|---|---|
| initial hemostasis rate | up to 24 months |
Countries
South Korea
Outcome results
None listed