Smoking Cessation
Conditions
Keywords
menthol cigarettes, smoking cessation
Brief summary
The primary aim of this study is to determine menthol smokers' perception, product preference, and pattern of use across six products including, mint-flavored nicotine gum; non-flavored nicotine gum; mentholated nicotine inhaler; and non-menthol nicotine inhaler. Participants will undergo an orientation and baseline assessment followed by a 2-week product sampling phase. At the end of the 2 weeks of sampling, subjects will select a product to use during the following 2-week smoking cessation phase. This 2-week abstinence phase is followed by one week of abrupt withdrawal of the product. This study design was successfully used in a study we conducted that examined the smokers' preference for a variety or oral tobacco products.
Interventions
OTHERNon-flavored 2mg nicotine gum
OTHERNon-flavored 4mg nicotine gum
OTHERMint-flavored 2mg nicotine gum
OTHERMint-flavored 4mg nicotine gum
OTHERNon-flavored nicotine inhaler
OTHERMint-flavored nicotine ihaler
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Self-identified as African American or Black; * Aged 18 years or older; * High school graduate or GED; * Smoking at least 10 cigarettes daily for the past year; * Usually smoked mentholated cigarette brand (greater than 80% of the time) in the past two years; * Good physical health (no unstable medical condition); * No contraindications for nicotine inhaler or gum use, such as mouth sores or significant dental or jaw problems; * Stable, good health.
Exclusion criteria
* Recent unstable or untreated psychiatric diagnosis including substance abuse, as determined by the DSM-IV criteria; * Currently using other tobacco or nicotine products other than cigarettes; * Pregnant or nursing.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Product preference for nicotine replacement | 6 weeks | To determine menthol smokers' product perception and preference across 6 different types of products with varying mint content. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Nicotine content preference | 6 weeks | To determine menthol smokers' product perception and preference across 6 different types of products with varying nicotine content. |
Countries
United States
Outcome results
None listed