Gonorrhea and Chlamydia HIV-infected Men Who Have Sex With Men

Prevalence of Gonorrhea and Chlamydia Infections in Multiple Anatomical Sites in HIV-infected Men Who Have Sex With Men at an HIV Clinic in Omaha, Nebraska

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02019771

Enrollment

150

Registered

2013-12-24

Start date

2014-03-07

Completion date

2014-10-01

Last updated

2023-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chlamydia, Gonorrhea, HIV Infection

Keywords

HIV Infection, Men who have sex with men, Chlamydia, Gonorrhea

Brief summary

This study will estimate the rates of asymptomatic Chlamydia and/or Gonorrhea in the oropharynx, rectum and urethra (urine) of HIV infected men who have sex with men at a specialty care center and compare it to the rates in Douglas County, using nucleic acid amplification tests.

Detailed description

Hypothesis: Men who have sex with men (MSM) are at higher risk for sexually transmitted diseases. Currently, free testing for sexually transmitted diseases is only being performed in urine samples. Investigators hypothesize that the rates of both gonorrhea and chlamydia will be higher when testing includes more than one anatomical site (rectum and oropharynx). The aim of the study is to estimate the rates of asymptomatic Chlamydia and/or Gonorrhea in the oropharynx, rectum and urethra (urine) of HIV infected men who have sex with men at the specialty care center of the University of Nebraska Medical Center and compare to the rates in Douglas County, using nucleic acid amplification tests.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

MALE

Age

19 Years to No maximum

Healthy volunteers

Inclusion criteria

* HIV infection * Men with history of sex with men (including transgender and bisexual) * Older than 19 years of age * Asymptomatic at the time of visit.

Exclusion criteria

* Active sexually transmitted disease symptoms in the oropharynx. * Recent treatment for Chlamydia or gonorrhea within 3 weeks. * Treatment with antibiotics active for Chlamydia or gonorrhea within the last 2 weeks: doxycycline, quinolones and azithromycin, and cefixime. * Women. * Inability to complete the questionnaire in English or Spanish.

Design outcomes

Primary

Measure	Time frame	Description
Chlamydia or gonorrhea infection	one day	Investigators will use nucleic acid amplification tests in urine, rectal and oropharyngeal swab specimens to detect asymptomatic chlamydia and/or gonorrhea infection

Secondary

Measure	Time frame	Description
accuracy for detecting infection when using one versus 2 versus 3 anatomical sites	1 day	Investigators will compare the proportion of infections detected by using only urine, only rectum, only oropharynx vs. using combined sites (urine and rectum, urine and oropharynx or oropharynx and rectum) vs. using all 3 sites.

Countries

United States

Outcome results