Atrial Fibrillation
Conditions
Keywords
atrial fibrillation, atrial flutter, catheter ablation, cavo-tricuspid isthmus block
Brief summary
Prospective Randomized Study on Clinical Effectiveness of Carvo-Tricuspid Isthmus (CTI) Block in Patients with Paroxysmal Atrial Fibrillation (PAF) will be performed. Study will be composed with two arms including 4 pulmonary vein isolation and pulmonary vein isolation with CTI block. After that all patients will be followed up by HRS(Heart Rhythm Society) 2010 expert consensus guideline.
Interventions
PROCEDUREPVI, CTI block
* PVI (pulmonary isolation) * Catheter ablation of cavo-tricuspid isthmus line for treatment of atrial fibrillation Catheter is inserted into inferior venacava (IVC) and right atrium (RA) via femoral vein. And the procedure is to block bidirectionally between inferior venacava (IVC) and the annulus of tricuspid valve (TV) by using electrical energy of catheter tip.
PROCEDUREPVI
PVI (pulmonary isolation)
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* patients with documented AF * Drug refractory AF * Non-valvular AF * No structural cardiac disease * No intracardiac thrombi in cardiac CT and TEE
Exclusion criteria
* permanent AF refractory to electrical cardioversion * LA size \>55 mm as measured by echocardiography * AF with valvular disease * associated structural heart disease other than left ventricular hypertrophy * prior AF ablation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence of Atrial fibrillation (AF free survival) | 3 month after catheter ablation | clinical recurrence of AF after catheter ablation |
Countries
South Korea
Outcome results
None listed