Oral Cavity Squamous Cell Carcinoma, Treated With Surgery
Conditions
Keywords
oral cavity squamous cell carcinoma, head and neck cancer, oral cancer
Brief summary
The harmonic scalpel is a tool that may reduce operative blood loss. Some studies also indicate it may result in faster surgery. A recently published randomized study from our group shows the harmonic scalpel reduces blood loss in neck dissection but it did not offer any reduction in OR time. The present study investigates the utility of the harmonic scalpel in resections involving removal of oral cavity tissues as well as the neck. Oral cavity resections are especially prone to blood loss and we believe the harmonic scalpel will confer benefits in this type of surgery, potentially reducing the need for blood transfusion.
Interventions
PROCEDUREsurgical resection
neck dissection and tumour resection will be performed either with or without the harmonic scalpel as an adjunct.
Sponsors
University of Calgary
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \> 18 years * oral cavity scc * primary surgery including either uni or bilateral neck dissection (levels I-IV)
Exclusion criteria
* previous treatment for head and neck cancer * unable or unwilling to give informed consent * history of bleeding disorder * other contraindications to surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood loss | intraoperative |
Secondary
| Measure | Time frame |
|---|---|
| operating time | intraoperative |
Countries
Canada
Outcome results
None listed