Infection
Conditions
Keywords
Liver Cirrhosis,Infection, Impedance, Body Composition
Brief summary
Patients with acute decompensation of cirrhosis, or acute on chronic liver failure often present with malnutrition, and due to the in-hospital stay, their nutritional intake can vary widely, with several periods of fasting, and sometimes insufficient nutritional support. Therefore patients are prone to develop malnutrition or, the already present malnutrition worsens its status. Our aim is to evaluate the daily changes in nutritional status in patients with acute decompensation of cirrhosis and evaluate the changes in plasma and serum biomarkers.
Interventions
OTHERNutritional assessment
Daily nutritional assessment with bioelectrical impedance vector analysis, phase angle and mid-arm muscle circumference
Sponsors
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age 18-75 years old * Patients with confirmed cirrhosis. * Any etiology * Hospitalized with acute decompensation of cirrhosis * Signed informed consent
Exclusion criteria
* Pregnancy * Amputation * Incomplete data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in nutritional status | Daily measurement up to 30 days | Nutritional status will be measured with bioelectrical impedance analysis (Vector and phase angle) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of inflammatory cytokines | Samples will be collected at the baseline evaluation. | ELISA's test |
Countries
Mexico
Contacts
Primary ContactAldo Torre Delgadillo, M.D. M.Sc
Backup ContactAstrid Ruiz-Margáin, M.Sc
Outcome results
None listed