Prospective Observational Study of Disease Progression in Chronic Hepatitis C

Observational Study of Disease Progression and Risk Factors in Chronic Hepatitis C Caused by Plasma Donation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02011932

Enrollment

133

Registered

2013-12-16

Start date

2010-07-31

Completion date

2030-07-31

Last updated

2013-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disease Progression, Hepatitis C, Chronic, Liver Cirrhosis

Brief summary

The purpose of this study is to determine the progression of chronic hepatitis C patients infected by paid plasma donation,and explore the possible pathogenic mechanisms of disease progression in chronic hepatitis C.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* All these patients had a definite history of regular plasma donations with repeated blood cell re-transfusions. * The Hepatitis C Virus antibody was positive. * All patients did not receive interferon therapy before being recruited.

Exclusion criteria

* Patients with evidences for other forms of liver diseases. * The coinfection with hepatitis B virus or other virus.

Design outcomes

Primary

Measure	Time frame
Fibrosis progression rate	20 years
The incidence of cirrhosis	20 years
Risk factors for the occurrence of cirrhosis	20 years

Secondary

Measure	Time frame
The incidence of hepatocellular carcinoma	20 years
Number of participants with chronic hepatitis C-related complications	20 years

Outcome results