Depression, Kidney Failure, Chronic, Quality of Life
Conditions
Brief summary
Depression is common in end-stage renal disease (ESRD) patients and has a negative effect on the quality of life, functional ability, and mortality, with a prevalence rate as high as 20-25%. However, it is hard to use anti-depressant due to the safety issue, and there has been little data so far particularly in terms of randomized clinical trials. Here, we investigate the effect of cognitive-behavioral group therapy for enhancing mental health and quality of life in patients with ESRD.
Interventions
BEHAVIORALCognitive-behavioral group therapy
Sponsors
Seoul National University Boramae Hospital
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with end-stage renal disease : on hemodialysis more than 3 months * Patients with BDI-II score \>= 15 points * Adult with age \>= 20 years old * Patients who were able to understand and willing to sign the written informed consent
Exclusion criteria
* Patients on hemodialysis due to acute kidney injury * Patients who are on admission * Patients who are undergoing chemotherapy or radiation therapy due to progressive malignant disease * Patients who are planning kidney transplantation within few months * Patients with cognitive dysfunction, mental retardation, and drug addict * Patients who are unavailable for adequate communication with researchers * Patients who changed anti-depressive agent or dose within 2 months before/after the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Beck Depression Inventory-II (BDI-II) score | 3 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Secondary assessment tools for depression,anxiety, and quality of life | 3 months | Hamilton Depression Rating Scale (HAMD-17): assessment for depressive mood |
Countries
South Korea
Outcome results
None listed